Proactive Paws Primitive Probiotics (45g) by Dr Karen Becker. Next gen probiotics from wild wolves, canine specific strains, soil based organism

  • Expiry date: May 31, 2028
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Developed by world-renowned veterinarian Dr Karen Becker, Proactive Paws introduces Primitive Probiotics — a species-specific formulation designed for the canine microbiome as nature intended.

Species-Specific Gut Health for Dogs

The Future of Pet Probiotics Starts Here

Primitive Probiotics™ combines ancestral strains from wild wolves, species-specific strains from healthy domestic dogs, and ultra-resilient soil-based organisms (SBOs). This unique 3-in-1 formula delivers unmatched microbial diversity and survives stomach acid to truly transform your dog’s gut health. PRIMITIVE PROBIOTICS™ is ideal for:

  • Dogs with diarrhea, soft stools, or excessive gasDogs recovering from antibiotics, illness, or stress
  • Dogs receiving heartworm parasiticides or flea/tick medications that can alter microbiota
  • Dogs with anxiety, aggression, or sleep issues
  • Seniors needing immune and cognitive support
  • Puppies building a resilient microbiome from the start

Not all probiotics are created equal. Most pet probiotics on the market are human strains, never adapted to the metabolic, immune, or thermal environment of dogs. They’re not designed to survive the journey through a carnivore’s GI tract and accomplish a specific purpose. And many lack evidence of efficacy in the species they’re sold for.

That’s why Dr Karen Becker, Co-author of the #1 NY Times selling book, the Forever Dog developed PRIMITIVE PROBIOTICS™, a radically different, science-driven approach to rebuilding and maintaining your dog’s microbiome using the very strains nature intended: from wild wolves, healthy domestic dogs, and living soil.

Emerging research now confirms that species-specific probiotics, isolated from healthy members of the same species, offer more targeted benefits. These strains are naturally adapted to the host animal’s microbiome, pH, bile levels, temperature, and immune landscape.

1. Ancestral Strains

These strains are isolated from wild wolves and represent the ancient microbial allies that dogs evolved with: robust, immune-priming, and genetically aligned with the canine body.

2. Species-Specific Strains

Sourced from healthy domestic dogs, these strains are uniquely adapted to the stressors and diets of modern life. They’re highly colonizable and provide targeted support for digestion, immunity, and stress tolerance.

3. Soil-Based Organisms (SBOs)

Spore-forming probiotics like Bacillus subtilis and Bacillus clausii are natural survivors. They resist heat, stomach acid, and antibiotics; modulating inflammation and restoring balance when your dog needs it most.

This triad is more than just a probiotic; it’s a complete microbiome restoration system. Together, they create a truly adaptive, robust, and functional microbiome for modern dogs.

What can you expect?

  • 24 - 48 hours: Noticeably firmer stools, less gas, and less bloating
  • 1 - 2 weeks: Calmer mood and better appetite 
  • 4 + weeks: Stronger immunity, more energy, improved sleep, and better resilience

Why do vets trust Primitive Probiotics™?

  • Designed by a functional medicine veterinarian and microbiome scientists 
  • Built for the canine gut, not repurposed from human formulas
  • Third-party tested for purity, viability, and shelf stability
  • Free from fillers, preservatives, or synthetic flavours 
  • Safe for long-term use in all breeds and life stages
  • Safety-certified: evaluated under FDA GRAS and Health Canada List C veterinary health standards
  • Clinically backed: supported by multi-site trails using real-world canine models, not rodents or petri dishes 
  • Manufactured in the USA in a GMP-certified facility, following strict quality and safety guidelines to ensure purity, potency, and consistency

More Information

Most pet probiotics are not truly dog‑specific, often using human strains that are poorly adapted to the canine digestive tract, immune system, bile environment, and body temperature.

PRIMITIVE PROBIOTICS™ uses species-aligned, healthy microbes sourced from wild canids, healthy domestic dogs, and soil-based organisms—mirroring how dogs naturally evolved to acquire beneficial bacteria.

A three‑ecosystem approach restores microbial diversity, combining ancestral strains, modern canine strains, and resilient soil‑based organisms to create a stable, functional, and adaptable gut microbiome.

Clinically studied strains deliver targeted benefits, including improved stool quality, reduced diarrhea and gas, stronger immunity, calmer behavior, allergy relief, and better resilience after antibiotics or stress.

The formula is science‑backed, safe, and results‑driven, third‑party tested, free from fillers and prebiotics, suitable for all life stages, and designed specifically for the modern dog’s biological needs.

Many microbiome-damaging insults disrupt serotonin production in the gut, making anxiety and behavior problems worse. This is the first veterinary-formulated product that blends LP815, a patented, calming strain, with S. boulardii, the strain recommended for use during antibiotic therapy to reduce microbiome damage.

More information on https://www.proactivepaws.com/products/primitive-probiotics?variant=53259728552301

Species-Specific Gut Health for Dogs

PRIMITIVE PROBIOTICS™ is a radically different, science-driven approach to rebuilding and maintaining your dog’s microbiome using the very strains nature intended: from wild canids, healthy domestic dogs, and living soil.

Every strain was selected for its specific functional benefit and survivability in the canine gastrointestinal tract.

Lactobacillus fermentum K9-2
Improves stool quality, supports gut barrier integrity, and reduces inflammation.

Lactobacillus casei K9-1
Balances gut flora, reduces Clostridium spp., and works synergistically with L. fermentum.

Lactobacillus reuteri PCR7
Produces reuterin (a natural antimicrobial), supports immune modulation and oral health.

Pediococcus acidilactici PCLL01
Survives gastric acid, reduces gas and diarrhea, supports microbial diversity.

Bifidobacterium spp.
Ferments fiber into SCFAs, enhances immunity, reduces gut inflammation in dogs.

Optibiome® BS50 Bacillus subtilis
Improves stool consistency, nutrient digestion, and antioxidant status.

MuniSpore® Bacillus clausii CS108
Resistant to antibiotics and stomach acid; reduces diarrhea and supports gut and respiratory immunity.

Lactobacillus rhamnosus GG
One of the world’s most researched strains; reduces allergic reactivity and supports the gut-brain axis.

Saccharomyces boulardii
Probiotic yeast that halts diarrhea, protects the gut lining, and reduces inflammation.

Lactiplantibacillus plantarum LP815 (GABA Probiotic)
Produces GABA—a natural calming compound that regulates mood, sleep, and aggression

-- What’s NOT in PRIMITIVE PROBIOTICS --

With gut issues like small intestine bacterial overgrowth (SIBO), prebiotics can worsen symptoms by fueling bacteria in the small intestine, increasing bloating, gas, and discomfort. In contrast, a dog gut health supplement with targeted probiotics may help rebalance microbes, reduce harmful species, and support the gut barrier without feeding the overgrowth. Strains like Saccharomyces boulardii and certain soil-based spore-formers are less likely to drive fermentation and may crowd out problematic microbes while calming inflammation. For this reason, we don’t include prebiotics in our formula.

FAQs

Q. What makes Primitive Probiotics™ different from other dog probiotics?

Primitive Probiotics™ combines ancestral strains from wild wolves, species-specific strains from healthy domestic dogs, and ultra-resilient soil-based organisms (SBOs). This unique 3-in-1 formula delivers unmatched microbial diversity and survives stomach acid to truly transform your dog's gut health

Q. How long before I start to see results?

Most dogs experience better stool quality and less gas within 24 - 48 hours. Calmer moods and reduced itching typically appear within 1 - 2 weeks, with stronger immunity and sustained energy by week 4.

Q. Is Primitive Probiotics™ safe for puppies and senior dogs?

Yes. It is vet-formulated and safe for dogs of all ages, including puppies building a strong microbiome and seniors needing extra digestive and immune support.

Q. Can this help my dog with anxiety or aggression issues?

Primitive Probiotics™ includes GABA-producing LP815, clinically shown to reduce anxiety, improve mood, and promote restful sleep, making it ideal for anxious or high-string dogs.

Q. If my dogs has taken or is taking antibiotics, when should I give Primitive Probiotics™?

If your dog has recently finished a course of antibiotics, give Primitive Probiotics with meals to help rebuild and restore the microbiome. If your dog is currently taking antibiotics, administer Primitive Probiotics at least 4 hours before or after the antibiotic dose - never at the same time - to ensure both work effectively.

Q. Why do you add organic pumpkin fibre in the formula?

Organic pumpkin fibre is a whole-food digestive superfood. With both soluble and insoluble fibre, it supports nutrient absorption, regular stools, and a balanced gut environment where probiotics thrive. Rich in vitamins, minerals, and antioxidants, pumpkin also nourishes the gut lining, calms inflammation, and strengthens immune defenses. Unlike isolated probiotics that can trigger SIBO, pumpkin is gentle, effective, and biologically appropriate, making it the ideal partner for probiotics.

Active Ingredients per 1 Scoop (1.5g):

Organic Pumpkin Powder (Cucurbita moschata) 1.38 g

Canine Heritage Blend - Dog Strains  600 Million CFU

Lactobacillus casei
Lactobacillus fermentum
Pediococcus acidilactici
Bifidobacterium bifidum
Bacillus subtilis

Non-Spore Forming Probiotics and Yeast Blend 200 Million CFU

Lactiplantibacillus plantarum LP815™
Saccharomyces boulardii
Lactobacillus rhamnosus

Soil-Based Probiotics Blend 150 Million CFU
OptiBiome BS50®
Bacillus subtilis
MuniSpore® Bacillus clausii

Canine Ancestral Blends - Wolf Strain 50 Million CFU
Lactobacillus reuteri
Lactobacillus brevis

Sprinkle the recommended amount directly onto food or a snack once daily.

For dogs with sensitive stomachs, start with half the suggested dose for the first few days and gradually increase to a full dose.

If using during antibiotic therapy, give the probiotic at least 4 hours before or after antibiotics to help protect beneficial bacteria. (based on 1 Billion CFU per 1.5 g serving)

Small Dogs: under 15 lbs - 1/2 scoop(0.75 g)
Medium Dogs: under 15-40 lbs - 1 scoop(1.5 g)
Large Dogs: under 40-80 lbs1 - 1/2 scoop(2.25 g)
Extra Large Dogs: over 80 lbs - 2 scoops(3 g)

Mission Statement

At Proactive Paws™, our mission is to support the restoration and preservation of health through veterinary-formulated, functional supplements for companion animals. Proactive Paws products are uncompromisingly made by human-grade standards. Rooted in science and fueled by compassion, our formulas are created to give every animal their best chance at a longer, healthier life.

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